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Phosphorylation of CDC25C by AMP-activated protein kinase mediates a metabolic checkpoint during cell-cycle G(2)/M-phase transition
From unicellular to multicellular organisms, cell-cycle progression is tightly coupled to biosynthetic and bioenergetic demands. Accumulating evidence has demonstrated the G(1)/S-phase transition as a key checkpoint where cells respond to their metabolic status and commit to replicating the genome....
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Publicado no: | J Biol Chem |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5892595/ https://ncbi.nlm.nih.gov/pubmed/29467227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001379 |
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