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Structural basis for antibody targeting of the broadly expressed microbial polysaccharide poly-N-acetylglucosamine
In response to the widespread emergence of antibiotic-resistant microbes, new therapeutic agents are required for many human pathogens. A non-mammalian polysaccharide, poly-N-acetyl-d-glucosamine (PNAG), is produced by bacteria, fungi, and protozoan parasites. Antibodies that bind to PNAG and its de...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5892565/ https://ncbi.nlm.nih.gov/pubmed/29449370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001170 |
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