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Structural basis for antibody targeting of the broadly expressed microbial polysaccharide poly-N-acetylglucosamine

In response to the widespread emergence of antibiotic-resistant microbes, new therapeutic agents are required for many human pathogens. A non-mammalian polysaccharide, poly-N-acetyl-d-glucosamine (PNAG), is produced by bacteria, fungi, and protozoan parasites. Antibodies that bind to PNAG and its de...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Soliman, Caroline, Walduck, Anna K., Yuriev, Elizabeth, Richards, Jack S., Cywes-Bentley, Colette, Pier, Gerald B., Ramsland, Paul A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892565/
https://ncbi.nlm.nih.gov/pubmed/29449370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001170
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