A Poly-N-Acetylglucosamine−Shiga Toxin Broad-Spectrum Conjugate Vaccine for Shiga Toxin-Producing Escherichia coli

Many pathogens produce the β-(1−6)-linked poly-N-acetylglucosamine (PNAG) surface polysaccharide that is being developed as a broadly protective antimicrobial vaccine. However, it is unknown whether systemically injected PNAG vaccines or antibodies would provide protective immunity against pathogens...

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Main Authors: Lu, Xi, Skurnik, David, Pozzi, Clarissa, Roux, Damien, Cywes-Bentley, Colette, Ritchie, Jennifer M., Munera, Diana, Gening, Marina L., Tsvetkov, Yury E., Nifantiev, Nikolay E., Waldor, Matthew K., Pier, Gerald B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Microbiology 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977355/
https://ncbi.nlm.nih.gov/pubmed/24667709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00974-14
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