Temporal, Diagnostic, and Tissue-Specific Regulation of NRG3 Isoform Expression in Human Brain Development and Affective Disorders

OBJECTIVE: Genes implicated in schizophrenia are enriched in networks differentially regulated during human CNS development. Neuregulin 3 (NRG3), a brain-enriched neurotrophin, undergoes alternative splicing and is implicated in several neurological disorders with developmental origins. Isoform-spec...

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Detalhes bibliográficos
Publicado no:Am J Psychiatry
Main Authors: Paterson, Clare, Wang, Yanhong, Hyde, Thomas M., Weinberger, Daniel R., Kleinman, Joel E., Law, Amanda J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892449/
https://ncbi.nlm.nih.gov/pubmed/27771971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2016.16060721
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