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A Novel Association of Polymorphism in the ITGA4 Gene Encoding the VLA-4 α4 Subunit with Increased Risk of Alzheimer's Disease

Alzheimer's disease (AD) is the most prevalent cause of dementia in elderly people worldwide. Many studies support the hypothesis that the inflammation of the CNS contributes to the neurodegeneration and disease progression. The integrin molecule α4β1, also known as very late antigen 4 (VLA-4),...

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書誌詳細
出版年:Mediators Inflamm
主要な著者: Durmanova, Vladimira, Parnicka, Zuzana, Javor, Juraj, Minarik, Gabriel, Vrazda, Lubomir, Vaseckova, Barbora, Gmitterova, Karin, Kralova, Maria, Pecenak, Jan, Filipcik, Peter, Shawkatova, Ivana
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892238/
https://ncbi.nlm.nih.gov/pubmed/29769839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/7623823
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