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A Novel Association of Polymorphism in the ITGA4 Gene Encoding the VLA-4 α4 Subunit with Increased Risk of Alzheimer's Disease

Alzheimer's disease (AD) is the most prevalent cause of dementia in elderly people worldwide. Many studies support the hypothesis that the inflammation of the CNS contributes to the neurodegeneration and disease progression. The integrin molecule α4β1, also known as very late antigen 4 (VLA-4),...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Durmanova, Vladimira, Parnicka, Zuzana, Javor, Juraj, Minarik, Gabriel, Vrazda, Lubomir, Vaseckova, Barbora, Gmitterova, Karin, Kralova, Maria, Pecenak, Jan, Filipcik, Peter, Shawkatova, Ivana
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892238/
https://ncbi.nlm.nih.gov/pubmed/29769839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/7623823
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