A Novel Association of Polymorphism in the ITGA4 Gene Encoding the VLA-4 α4 Subunit with Increased Risk of Alzheimer's Disease

Alzheimer's disease (AD) is the most prevalent cause of dementia in elderly people worldwide. Many studies support the hypothesis that the inflammation of the CNS contributes to the neurodegeneration and disease progression. The integrin molecule α4β1, also known as very late antigen 4 (VLA-4),...

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Bibliografiske detaljer
Udgivet i:Mediators Inflamm
Main Authors: Durmanova, Vladimira, Parnicka, Zuzana, Javor, Juraj, Minarik, Gabriel, Vrazda, Lubomir, Vaseckova, Barbora, Gmitterova, Karin, Kralova, Maria, Pecenak, Jan, Filipcik, Peter, Shawkatova, Ivana
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892238/
https://ncbi.nlm.nih.gov/pubmed/29769839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/7623823
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