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Targeted isotretinoin in neuroblastoma: Kinetics, Genetics or Absorption

Isotretinoin (13-cis-retinoic acid; 13-cisRA) has been shown to significantly improve survival for children with high-risk neuroblastoma. Pharmacokinetics of isotretinoin may be negatively affected by the mode of drug administration and the dosing formula.

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Detalles Bibliográficos
Publicado en:Clin Cancer Res
Autor Principal: Matthay, Katherine K.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892183/
https://ncbi.nlm.nih.gov/pubmed/23209029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-3313
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