Genomic analysis of the origins and evolution of multicentric diffuse lower-grade gliomas

BACKGROUND: Rare multicentric lower-grade gliomas (LGGs) represent a unique opportunity to study the heterogeneity among distinct tumor foci in a single patient and to infer their origins and parallel patterns of evolution. METHODS: In this study, we integrate clinical features, histology, and immun...

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Publicado en:Neuro Oncol
Main Authors: Hayes, Josie, Yu, Yao, Jalbert, Llewellyn E, Mazor, Tali, Jones, Lindsey E, Wood, Matthew D, Walsh, Kyle M, Bengtsson, Henrik, Hong, Chibo, Oberndorfer, Stefan, Roetzer, Thomas, Smirnov, Ivan V, Clarke, Jennifer L, Aghi, Manish K, Chang, Susan M, Nelson, Sarah J, Woehrer, Adelheid, Phillips, Joanna J, Solomon, David A, Costello, Joseph F
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
Assuntos:
Basic and Translational Investigations
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892142/
https://ncbi.nlm.nih.gov/pubmed/29077933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox205
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