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Genomic analysis of the origins and evolution of multicentric diffuse lower-grade gliomas

BACKGROUND: Rare multicentric lower-grade gliomas (LGGs) represent a unique opportunity to study the heterogeneity among distinct tumor foci in a single patient and to infer their origins and parallel patterns of evolution. METHODS: In this study, we integrate clinical features, histology, and immun...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Hayes, Josie, Yu, Yao, Jalbert, Llewellyn E, Mazor, Tali, Jones, Lindsey E, Wood, Matthew D, Walsh, Kyle M, Bengtsson, Henrik, Hong, Chibo, Oberndorfer, Stefan, Roetzer, Thomas, Smirnov, Ivan V, Clarke, Jennifer L, Aghi, Manish K, Chang, Susan M, Nelson, Sarah J, Woehrer, Adelheid, Phillips, Joanna J, Solomon, David A, Costello, Joseph F
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892142/
https://ncbi.nlm.nih.gov/pubmed/29077933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox205
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