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Involvement of the NFX1-repressor complex in PKC-δ-induced repression of hTERT transcription

The human telomerase reverse transcriptase (hTERT) gene encodes an enzyme responsible for maintaining the integrity of chromosomal ends. hTERT plays a key role in cellular immortalization, tumorigenesis and the progression of cancer. Previously, we reported that hTERT repression is required for the...

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Dades bibliogràfiques
Publicat a:J Biochem
Autors principals: Yamashita, Shuntaro, Fujii, Kaoru, Zhao, Chong, Takagi, Hiroshi, Katakura, Yoshinori
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892129/
https://ncbi.nlm.nih.gov/pubmed/27311997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jb/mvw038
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