Alternative splicing of human telomerase reverse transcriptase in gliomas and its modulation mediated by CX-5461

BACKGROUND: Glioma is a heterogeneous, invasive primary brain tumor with a wide range of patient survival and a lack of reliable prognostic biomarkers. Human telomerase reverse transcriptase (hTERT) has been reported in the presence of multiple transcripts in various tumor systems. The biological fu...

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Vydáno v:J Exp Clin Cancer Res
Hlavní autoři: Li, Guihong, Shen, Jing, Cao, Junguo, Zhou, Guangtong, Lei, Ting, Sun, Yuxue, Gao, Haijun, Ding, Yaonan, Xu, Weidong, Zhan, Zhixin, Chen, Yong, Huang, Haiyan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891986/
https://ncbi.nlm.nih.gov/pubmed/29631594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0749-8
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