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Transcriptional activator DOT1L putatively regulates human embryonic stem cell differentiation into the cardiac lineage
BACKGROUND: Commitment of pluripotent stem cells into differentiated cells and associated gene expression necessitate specific epigenetic mechanisms that modify the DNA and corresponding histone proteins to render the chromatin in an open or closed state. This in turn dictates the associated genetic...
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| Publicado no: | Stem Cell Res Ther |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5891944/ https://ncbi.nlm.nih.gov/pubmed/29631608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-0810-8 |
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