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Transcriptional activator DOT1L putatively regulates human embryonic stem cell differentiation into the cardiac lineage

BACKGROUND: Commitment of pluripotent stem cells into differentiated cells and associated gene expression necessitate specific epigenetic mechanisms that modify the DNA and corresponding histone proteins to render the chromatin in an open or closed state. This in turn dictates the associated genetic...

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Bibliografski detalji
Izdano u:Stem Cell Res Ther
Glavni autori: Pursani, Varsha, Bhartiya, Deepa, Tanavde, Vivek, Bashir, Mohsin, Sampath, Prabha
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891944/
https://ncbi.nlm.nih.gov/pubmed/29631608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-0810-8
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