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A Bayesian Basket Trial Design Using a Calibrated Bayesian Hierarchical Model
BACKGROUND: The basket trial evaluates the treatment effect of a targeted therapy in patients with the same genetic or molecular aberration, regardless of their cancer types. Bayesian hierarchical modeling has been proposed to adaptively borrow information across cancer types to improve the statisti...
Gardado en:
| Publicado en: | Clin Trials |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5891374/ https://ncbi.nlm.nih.gov/pubmed/29499621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774518755122 |
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