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Antimalarial drug mefloquine inhibits nuclear factor kappa B signaling and induces apoptosis in colorectal cancer cells

Nuclear factor kappa B (NF‐κB) signaling pathway is activated in many colorectal cancer (CRC) cells and in the tumor microenvironment, which plays a critical role in cancer initiation, development, and response to therapies. In the present study, we found that the widely used antimalarial drug meflo...

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Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Xu, Xin, Wang, Jun, Han, Kunkun, Li, Shaoyan, Xu, Feng, Yang, Yili
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891192/
https://ncbi.nlm.nih.gov/pubmed/29453896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13540
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