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Modulation of AKR1C2 by curcumin decreases testosterone production in prostate cancer

Intratumoral androgen biosynthesis has been recognized as an essential factor of castration‐resistant prostate cancer. The present study investigated the effects of curcumin on the inhibition of intracrine androgen synthesis in prostate cancer. Human prostate cancer cell lines, LNCaP and 22Rv1 cells...

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Détails bibliographiques
Publié dans:Cancer Sci
Auteurs principaux: Ide, Hisamitsu, Lu, Yan, Noguchi, Takahiro, Muto, Satoru, Okada, Hiroshi, Kawato, Suguru, Horie, Shigeo
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891173/
https://ncbi.nlm.nih.gov/pubmed/29369461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13517
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