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Modulation of AKR1C2 by curcumin decreases testosterone production in prostate cancer

Intratumoral androgen biosynthesis has been recognized as an essential factor of castration‐resistant prostate cancer. The present study investigated the effects of curcumin on the inhibition of intracrine androgen synthesis in prostate cancer. Human prostate cancer cell lines, LNCaP and 22Rv1 cells...

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Dettagli Bibliografici
Pubblicato in:Cancer Sci
Autori principali: Ide, Hisamitsu, Lu, Yan, Noguchi, Takahiro, Muto, Satoru, Okada, Hiroshi, Kawato, Suguru, Horie, Shigeo
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891173/
https://ncbi.nlm.nih.gov/pubmed/29369461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13517
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