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Understanding intratumor heterogeneity by combining genome analysis and mathematical modeling
Cancer is composed of multiple cell populations with different genomes. This phenomenon called intratumor heterogeneity (ITH) is supposed to be a fundamental cause of therapeutic failure. Therefore, its principle‐level understanding is a clinically important issue. To achieve this goal, an interdisc...
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Publicado no: | Cancer Sci |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley and Sons Inc.
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5891172/ https://ncbi.nlm.nih.gov/pubmed/29352488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13510 |
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