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A transcriptional serenAID: the role of noncoding RNAs in class switch recombination

During an immune response, activated B cells may undergo class switch recombination (CSR), a molecular rearrangement that allows B cells to switch from expressing IgM and IgD to a secondary antibody heavy chain isotype such as IgG, IgA or IgE. Secondary antibody isotypes provide the adaptive immune...

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Detalhes bibliográficos
Publicado no:Int Immunol
Main Authors: Yewdell, William T., Chaudhuri, Jayanta
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890902/
https://ncbi.nlm.nih.gov/pubmed/28535205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxx027
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