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Identification of novel mutations associated with cycloserine resistance in Mycobacterium tuberculosis
OBJECTIVES: d-Cycloserine is an important second-line drug used to treat MDR- and XDR-TB. However, the mechanisms of resistance to d-cycloserine are not well understood. Here we investigated the molecular basis of d-cycloserine resistance using in vitro-isolated resistant mutants. METHODS: Mycobacte...
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| Publicat a: | J Antimicrob Chemother |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5890659/ https://ncbi.nlm.nih.gov/pubmed/28961957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx316 |
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