Identification of novel mutations associated with cycloserine resistance in Mycobacterium tuberculosis

OBJECTIVES: d-Cycloserine is an important second-line drug used to treat MDR- and XDR-TB. However, the mechanisms of resistance to d-cycloserine are not well understood. Here we investigated the molecular basis of d-cycloserine resistance using in vitro-isolated resistant mutants. METHODS: Mycobacte...

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Udgivet i:J Antimicrob Chemother
Main Authors: Chen, Jiazhen, Zhang, Shuo, Cui, Peng, Shi, Wanliang, Zhang, Wenhong, Zhang, Ying
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890659/
https://ncbi.nlm.nih.gov/pubmed/28961957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx316
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