Uromodulin rs4293393 T>C variation is associated with kidney disease in patients with type 2 diabetes

BACKGROUND & OBJECTIVES: Uromodulin, a UMOD gene encoded glycoprotein is synthesized exclusively in renal tubular cells and released into urine. Mutations lead to uromodulin misfolding and retention in the kidney, where it might stimulate cells of immune system to cause inflammation and progress...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Indian J Med Res
Prif Awduron: Kumar, Vinod, Yadav, Ashok Kumar, Kumar, Vivek, Bhansali, Anil, Jha, Vivekanand
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Medknow Publications & Media Pvt Ltd 2017
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890591/
https://ncbi.nlm.nih.gov/pubmed/29578190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/ijmr.IJMR_919_16
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