Uromodulin rs4293393 T>C variation is associated with kidney disease in patients with type 2 diabetes

BACKGROUND & OBJECTIVES: Uromodulin, a UMOD gene encoded glycoprotein is synthesized exclusively in renal tubular cells and released into urine. Mutations lead to uromodulin misfolding and retention in the kidney, where it might stimulate cells of immune system to cause inflammation and progress...

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Bibliografiske detaljer
Udgivet i:Indian J Med Res
Main Authors: Kumar, Vinod, Yadav, Ashok Kumar, Kumar, Vivek, Bhansali, Anil, Jha, Vivekanand
Format: Artigo
Sprog:Inglês
Udgivet: Medknow Publications & Media Pvt Ltd 2017
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890591/
https://ncbi.nlm.nih.gov/pubmed/29578190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/ijmr.IJMR_919_16
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