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Characterization of phenyl pyrimidine derivatives that inhibit cytomegalovirus immediate-early gene expression

BACKGROUND: Previously, we established a reporter cell line for human cytomegalovirus and screened anti-human cytomegalovirus compounds using the cell line. In this study, we characterized one of the identified compounds, 2,4-diamino-6–(4-methoxyphenyl)pyrimidine (coded as 35C10). METHODS: 50% Effec...

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Détails bibliographiques
Publié dans:Antivir Chem Chemother
Auteurs principaux: Yamada, Koh-Hei, Majima, Ryuichi, Yamaguchi, Toyofumi, Inoue, Naoki
Format: Artigo
Langue:Inglês
Publié: SAGE Publications 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890547/
https://ncbi.nlm.nih.gov/pubmed/29546767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040206618763193
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