Acquisition of N-Glycosylation Sites in Immunoglobulin Heavy Chain Genes During Local Expansion in Parotid Salivary Glands of Primary Sjögren Patients

Previous studies revealed high incidence of acquired N-glycosylation sites acquired N-glycosylation sites in RNA transcripts encoding immunoglobulin heavy variable region (IGHV) 3 genes from parotid glands of primary Sjögren’s syndrome (pSS) patients. In this study, next generation sequencing was us...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Visser, Annie, Doorenspleet, Marieke E., de Vries, Niek, Spijkervet, Fred K. L., Vissink, Arjan, Bende, Richard J., Bootsma, Hendrika, Kroese, Frans G. M., Bos, Nicolaas A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890187/
https://ncbi.nlm.nih.gov/pubmed/29662487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00491
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