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Activation of the NLRP3 Inflammasome Pathway by Uropathogenic Escherichia coli Is Virulence Factor-Dependent and Influences Colonization of Bladder Epithelial Cells

The NLRP3 inflammasome and IL-1β release have recently been suggested to be important for the progression of urinary tract infection (UTI). However, much is still unknown regarding the interaction of UPEC and the NLRP3 inflammasome. The purpose of this study was to elucidate what virulence factors u...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Demirel, Isak, Persson, Alexander, Brauner, Annelie, Särndahl, Eva, Kruse, Robert, Persson, Katarina
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890162/
https://ncbi.nlm.nih.gov/pubmed/29662840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2018.00081
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