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Activation of NLRP3 by uropathogenic Escherichia coli is associated with IL-1β release and regulation of antimicrobial properties in human neutrophils

The NLRP3 inflammasome and IL-1β have recently been linked to the severity of uropathogenic Escherichia coli (UPEC)-mediated urinary tract infection (UTI). However, not much is known about the contribution of NLRP3 to the antimicrobial properties of neutrophils and the release of IL-1β during UPEC i...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Demirel, Isak, Persson, Alexander, Brauner, Annelie, Särndahl, Eva, Kruse, Robert, Persson, Katarina
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736892/
https://ncbi.nlm.nih.gov/pubmed/33318544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78651-1
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