Targeting Mycobacterium tuberculosis Antigens to Dendritic Cells via the DC-Specific-ICAM3-Grabbing-Nonintegrin Receptor Induces Strong T-Helper 1 Immune Responses

Tuberculosis remains a major global health problem and efforts to develop a more effective vaccine have been unsuccessful so far. Targeting antigens (Ags) to dendritic cells (DCs) in vivo has emerged as a new promising vaccine strategy. In this approach, Ags are delivered directly to DCs via antibod...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Velasquez, Lis Noelia, Stüve, Philipp, Gentilini, Maria Virginia, Swallow, Maxine, Bartel, Judith, Lycke, Nils Yngve, Barkan, Daniel, Martina, Mariana, Lujan, Hugo D., Kalay, Hakan, van Kooyk, Yvette, Sparwasser, Tim D., Berod, Luciana
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890140/
https://ncbi.nlm.nih.gov/pubmed/29662482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00471
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