Targeting Mycobacterium tuberculosis Antigens to Dendritic Cells via the DC-Specific-ICAM3-Grabbing-Nonintegrin Receptor Induces Strong T-Helper 1 Immune Responses

Tuberculosis remains a major global health problem and efforts to develop a more effective vaccine have been unsuccessful so far. Targeting antigens (Ags) to dendritic cells (DCs) in vivo has emerged as a new promising vaccine strategy. In this approach, Ags are delivered directly to DCs via antibod...

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Vydáno v:Front Immunol
Hlavní autoři: Velasquez, Lis Noelia, Stüve, Philipp, Gentilini, Maria Virginia, Swallow, Maxine, Bartel, Judith, Lycke, Nils Yngve, Barkan, Daniel, Martina, Mariana, Lujan, Hugo D., Kalay, Hakan, van Kooyk, Yvette, Sparwasser, Tim D., Berod, Luciana
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890140/
https://ncbi.nlm.nih.gov/pubmed/29662482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00471
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