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Duplicated TLR5 of zebrafish functions as a heterodimeric receptor
Toll-like receptor 5 (TLR5) of mammals, birds, and reptiles detects bacterial flagellin and signals as a homodimeric complex. Structural studies using truncated TLR5b of zebrafish confirm the homodimeric TLR5–flagellin interaction. Here we provide evidence that zebrafish (Danio rerio) TLR5 unexpecte...
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| Izdano u: | Proc Natl Acad Sci U S A |
|---|---|
| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5889648/ https://ncbi.nlm.nih.gov/pubmed/29555749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719245115 |
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