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Reconstitution of a Functional Toll-like Receptor 5 Binding Site in Campylobacter jejuni Flagellin

Bacterial flagellin is important for intestinal immune homeostasis. Flagellins from most species activate Toll-like receptor 5 (TLR5). The principal bacterial food-borne pathogen Campylobacter jejuni escapes TLR5 recognition, probably due to an alternate flagellin subunit structure. We investigated...

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Bibliografiske detaljer
Main Authors: de Zoete, Marcel R., Keestra, A. Marijke, Wagenaar, Jaap A., van Putten, Jos P. M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852954/
https://ncbi.nlm.nih.gov/pubmed/20164175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.070227
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