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Identification and biosynthesis of thymidine hypermodifications in the genomic DNA of widespread bacterial viruses

Certain viruses of bacteria (bacteriophages) enzymatically hypermodify their DNA to protect their genetic material from host restriction endonuclease-mediated cleavage. Historically, it has been known that virion DNAs from the Delftia phage ΦW-14 and the Bacillus phage SP10 contain the hypermodified...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lee, Yan-Jiun, Dai, Nan, Walsh, Shannon E., Müller, Stephanie, Fraser, Morgan E., Kauffman, Kathryn M., Guan, Chudi, Corrêa, Ivan R., Weigele, Peter R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889632/
https://ncbi.nlm.nih.gov/pubmed/29555775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714812115
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