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Identification and biosynthesis of thymidine hypermodifications in the genomic DNA of widespread bacterial viruses

Certain viruses of bacteria (bacteriophages) enzymatically hypermodify their DNA to protect their genetic material from host restriction endonuclease-mediated cleavage. Historically, it has been known that virion DNAs from the Delftia phage ΦW-14 and the Bacillus phage SP10 contain the hypermodified...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Lee, Yan-Jiun, Dai, Nan, Walsh, Shannon E., Müller, Stephanie, Fraser, Morgan E., Kauffman, Kathryn M., Guan, Chudi, Corrêa, Ivan R., Weigele, Peter R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889632/
https://ncbi.nlm.nih.gov/pubmed/29555775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714812115
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