SALL1 functions as a tumor suppressor in breast cancer by regulating cancer cell senescence and metastasis through the NuRD complex

BACKGROUND: SALL1 is a multi-zinc finger transcription factor that regulates organogenesis and stem cell development, but the role of SALL1 in tumor biology and tumorigenesis remains largely unknown. METHODS: We analyzed SALL1 expression levels in human and murine breast cancer cells as well as canc...

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Détails bibliographiques
Publié dans:Mol Cancer
Auteurs principaux: Ma, Chunling, Wang, Fang, Han, Bing, Zhong, Xiaoli, Si, Fusheng, Ye, Jian, Hsueh, Eddy C., Robbins, Lynn, Kiefer, Susan M., Zhang, Yanping, Hunborg, Pamela, Varvares, Mark A., Rauchman, Michael, Peng, Guangyong
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889587/
https://ncbi.nlm.nih.gov/pubmed/29625565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0824-y
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