Association of human mitochondrial lysyl-tRNA synthetase with HIV-1 GagPol does not require other viral proteins

In human, the cytoplasmic (cLysRS) and mitochondrial (mLysRS) species of lysyl-tRNA synthetase are encoded by a single gene. Following HIV-1 infection, mLysRS is selectively taken up into viral particles along with the three tRNA(Lys) isoacceptors. The GagPol polyprotein precursor is involved in thi...

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Bibliographic Details
Published in:Biochim Open
Main Authors: Kobbi, Lydia, Dias, José, Comisso, Martine, Mirande, Marc
Format: Artigo
Language:Inglês
Published: Elsevier 2016
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Research paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889485/
https://ncbi.nlm.nih.gov/pubmed/29632838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopen.2016.02.004
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