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Characterization of association of human mitochondrial lysyl-tRNA synthetase with HIV-1 Pol and tRNA(3)(Lys)

BACKGROUND: An important step in human immunodeficiency virus type 1 (HIV-1) replication is the packaging of tRNA(3)(Lys) from the host cell, which plays the role of primer RNA in the process of initiation of reverse transcription. The viral GagPol polyprotein precursor, and the human mitochondrial...

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Publicat a:BMC Biochem
Autors principals: Khoder-Agha, Fawzi, Dias, José M., Comisso, Martine, Mirande, Marc
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863373/
https://ncbi.nlm.nih.gov/pubmed/29562886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12858-018-0092-x
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