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Characterization of association of human mitochondrial lysyl-tRNA synthetase with HIV-1 Pol and tRNA(3)(Lys)

BACKGROUND: An important step in human immunodeficiency virus type 1 (HIV-1) replication is the packaging of tRNA(3)(Lys) from the host cell, which plays the role of primer RNA in the process of initiation of reverse transcription. The viral GagPol polyprotein precursor, and the human mitochondrial...

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Pubblicato in:BMC Biochem
Autori principali: Khoder-Agha, Fawzi, Dias, José M., Comisso, Martine, Mirande, Marc
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863373/
https://ncbi.nlm.nih.gov/pubmed/29562886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12858-018-0092-x
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