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Characterization of association of human mitochondrial lysyl-tRNA synthetase with HIV-1 Pol and tRNA(3)(Lys)

BACKGROUND: An important step in human immunodeficiency virus type 1 (HIV-1) replication is the packaging of tRNA(3)(Lys) from the host cell, which plays the role of primer RNA in the process of initiation of reverse transcription. The viral GagPol polyprotein precursor, and the human mitochondrial...

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Publicado en:BMC Biochem
Autores principales: Khoder-Agha, Fawzi, Dias, José M., Comisso, Martine, Mirande, Marc
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863373/
https://ncbi.nlm.nih.gov/pubmed/29562886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12858-018-0092-x
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