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The Development of a Unified Enantioselective, Convergent Synthetic Approach Toward the Furanobutenolide-Derived Polycyclic Norcembranoid Diterpenes: Asymmetric Formation of the Polycyclic Norditerpenoid Carbocyclic Core by Tandem Annulation Cascade

An enantioselective and diastereoselective approach toward the synthesis of the tetracyclic scaffold of the furanobutenolide-derived polycyclic norditerpenoids is described. Focusing on synthetic efforts toward ineleganolide, the synthetic approach utilizes a palladium-catalyzed enantioselective all...

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Pubblicato in:J Org Chem
Autori principali: Craig, Robert A., Smith, Russell C., Roizen, Jennifer L., Jones, Amanda C., Virgil, Scott C., Stoltz, Brian M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889334/
https://ncbi.nlm.nih.gov/pubmed/29464957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.7b02825
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