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Enantioselective, convergent synthesis of the ineleganolide core by a tandem annulation cascade

An enantioselective and diastereoselective approach toward the synthesis of the polycyclic norditerpenoid ineleganolide is disclosed. A palladium-catalyzed enantioselective allylic alkylation is employed to stereoselectively construct the requisite chiral tertiary ether and facilitate the synthesis...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Craig, II, Robert A., Roizen, Jennifer L., Smith, Russell C., Jones, Amanda C., Virgil, Scott C., Stoltz, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321630/
https://ncbi.nlm.nih.gov/pubmed/28239443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc03347d
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