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Nanopore Analysis of the 5-Guanidinohydantoin to Iminoallantoin Isomerization in Duplex DNA

In DNA, guanine oxidation yields diastereomers of 5-guanidinohydantoin (Gh) as one of the major products. In nucleosides and single-stranded DNA, Gh is in a pH-dependent equilibrium with its constitutional isomer iminoallantoin (Ia). Herein, the isomerization reaction between Gh and Ia was monitored...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Org Chem
Prif Awduron: Zeng, Tao, Fleming, Aaron M., Ding, Yun, Ren, Hang, White, Henry S., Burrows, Cynthia J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889331/
https://ncbi.nlm.nih.gov/pubmed/29490132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.8b00317
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