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Dysfunctional telomeres and hematological disorders

Telomere biology disorders, which are characterized by telomerase activity haploinsufficiency and accelerated telomere shortening, most commonly manifest as degenerative diseases. Tissues with high rates of cell turnover, such as those in the hematopoietic system, are particularly vulnerable to defe...

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Detalhes bibliográficos
Publicado no:Differentiation
Main Authors: Fiorini, Elena, Santoni, Andrea, Colla, Simona
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889327/
https://ncbi.nlm.nih.gov/pubmed/29331736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.diff.2018.01.001
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