Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes

Exosomes can mediate a dynamic method of communication between malignancies, including those sequestered in the central nervous system and the immune system. We sought to determine whether exosomes from glioblastoma (GBM)-derived stem cells (GSCs) can induce immunosuppression. We report that GSC-der...

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Dettagli Bibliografici
Pubblicato in:Oncoimmunology
Autori principali: Gabrusiewicz, Konrad, Li, Xu, Wei, Jun, Hashimoto, Yuuri, Marisetty, Anantha L., Ott, Martina, Wang, Fei, Hawke, David, Yu, John, Healy, Luke M., Hossain, Anwar, Akers, Johnny C., Maiti, Sourindra N., Yamashita, Shinji, Shimizu, Yuzaburo, Dunner, Kenneth, Zal, M. Anna, Burks, Jared K., Gumin, Joy, Nwajei, Felix, Rezavanian, Aras, Zhou, Shouhao, Rao, Ganesh, Sawaya, Raymond, Fuller, Gregory N., Huse, Jason T., Antel, Jack P., Li, Shulin, Cooper, Laurence, Sulman, Erik P., Chen, Clark, Geula, Changiz, Kalluri, Raghu, Zal, Tomasz, Heimberger, Amy B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2018
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889290/
https://ncbi.nlm.nih.gov/pubmed/29632728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1412909
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