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Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes

Exosomes can mediate a dynamic method of communication between malignancies, including those sequestered in the central nervous system and the immune system. We sought to determine whether exosomes from glioblastoma (GBM)-derived stem cells (GSCs) can induce immunosuppression. We report that GSC-der...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Oncoimmunology
المؤلفون الرئيسيون: Gabrusiewicz, Konrad, Li, Xu, Wei, Jun, Hashimoto, Yuuri, Marisetty, Anantha L., Ott, Martina, Wang, Fei, Hawke, David, Yu, John, Healy, Luke M., Hossain, Anwar, Akers, Johnny C., Maiti, Sourindra N., Yamashita, Shinji, Shimizu, Yuzaburo, Dunner, Kenneth, Zal, M. Anna, Burks, Jared K., Gumin, Joy, Nwajei, Felix, Rezavanian, Aras, Zhou, Shouhao, Rao, Ganesh, Sawaya, Raymond, Fuller, Gregory N., Huse, Jason T., Antel, Jack P., Li, Shulin, Cooper, Laurence, Sulman, Erik P., Chen, Clark, Geula, Changiz, Kalluri, Raghu, Zal, Tomasz, Heimberger, Amy B.
التنسيق: Artigo
اللغة:Inglês
منشور في: Taylor & Francis 2018
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889290/
https://ncbi.nlm.nih.gov/pubmed/29632728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1412909
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