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Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes

Exosomes can mediate a dynamic method of communication between malignancies, including those sequestered in the central nervous system and the immune system. We sought to determine whether exosomes from glioblastoma (GBM)-derived stem cells (GSCs) can induce immunosuppression. We report that GSC-der...

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書誌詳細
出版年:Oncoimmunology
主要な著者: Gabrusiewicz, Konrad, Li, Xu, Wei, Jun, Hashimoto, Yuuri, Marisetty, Anantha L., Ott, Martina, Wang, Fei, Hawke, David, Yu, John, Healy, Luke M., Hossain, Anwar, Akers, Johnny C., Maiti, Sourindra N., Yamashita, Shinji, Shimizu, Yuzaburo, Dunner, Kenneth, Zal, M. Anna, Burks, Jared K., Gumin, Joy, Nwajei, Felix, Rezavanian, Aras, Zhou, Shouhao, Rao, Ganesh, Sawaya, Raymond, Fuller, Gregory N., Huse, Jason T., Antel, Jack P., Li, Shulin, Cooper, Laurence, Sulman, Erik P., Chen, Clark, Geula, Changiz, Kalluri, Raghu, Zal, Tomasz, Heimberger, Amy B.
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889290/
https://ncbi.nlm.nih.gov/pubmed/29632728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1412909
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