Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes

Exosomes can mediate a dynamic method of communication between malignancies, including those sequestered in the central nervous system and the immune system. We sought to determine whether exosomes from glioblastoma (GBM)-derived stem cells (GSCs) can induce immunosuppression. We report that GSC-der...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Gabrusiewicz, Konrad, Li, Xu, Wei, Jun, Hashimoto, Yuuri, Marisetty, Anantha L., Ott, Martina, Wang, Fei, Hawke, David, Yu, John, Healy, Luke M., Hossain, Anwar, Akers, Johnny C., Maiti, Sourindra N., Yamashita, Shinji, Shimizu, Yuzaburo, Dunner, Kenneth, Zal, M. Anna, Burks, Jared K., Gumin, Joy, Nwajei, Felix, Rezavanian, Aras, Zhou, Shouhao, Rao, Ganesh, Sawaya, Raymond, Fuller, Gregory N., Huse, Jason T., Antel, Jack P., Li, Shulin, Cooper, Laurence, Sulman, Erik P., Chen, Clark, Geula, Changiz, Kalluri, Raghu, Zal, Tomasz, Heimberger, Amy B.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889290/
https://ncbi.nlm.nih.gov/pubmed/29632728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1412909
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