Interleukin 7-expressing fibroblasts promote breast cancer growth through sustenance of tumor cell stemness

The tumor microenvironment harbors cancer-associated fibroblasts that function as major modulators of cancer progression. Here, we assessed to which extent distinct cancer-associated fibroblast subsets impact mammary carcinoma growth and cancer cell stemness in an orthotopic murine model. We found t...

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Dettagli Bibliografici
Pubblicato in:Oncoimmunology
Autori principali: Boesch, Maximilian, Onder, Lucas, Cheng, Hung-Wei, Novkovic, Mario, Mörbe, Urs, Sopper, Sieghart, Gastl, Guenther, Jochum, Wolfram, Ruhstaller, Thomas, Knauer, Michael, Ludewig, Burkhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2018
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889213/
https://ncbi.nlm.nih.gov/pubmed/29632733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1414129
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