A targeted immunotherapy approach for HER2/neu transformed tumors by coupling an engineered effector domain with interferon-γ

Despite substantial clinical progress with targeted therapies, current antibody-based approaches have limited efficacy at controlling HER2/neu-positive breast cancers, especially in the absence of chemotherapies. Previously, we showed that the combination of IFNγ and anti-HER2/neu antibody synergist...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: Zhang, Hongtao, Lam, Lian, Nagai, Yasuhiro, Zhu, Zhiqiang, Chen, Xi, Ji, Mei Q., Greene, Mark I.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889208/
https://ncbi.nlm.nih.gov/pubmed/29632709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1300739
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