Dynamic changes of the normal B lymphocyte repertoire in CLL in response to ibrutinib or FCR chemo-immunotherapy

Using next-generation immunoglobulin (IGH) sequencing and flow cytometry, we characterized the composition, diversity and dynamics of non-malignant B cells in patients undergoing treatment with the Bruton tyrosine kinase (BTK) inhibitor ibrutinib or chemo-immunotherapy with fludarabine, cyclophospha...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: Schliffke, Simon, Sivina, Mariela, Kim, Ekaterina, von Wenserski, Lisa, Thiele, Benjamin, Akyüz, Nuray, Falker-Gieske, Clemens, Statovci, Donjete, Oberle, Anna, Thenhausen, Toni, Krohn-Grimberghe, Artus, Bokemeyer, Carsten, Jain, Nitin, Estrov, Zeev, Ferrajoli, Alessandra, Wierda, William, Keating, Michael, Burger, Jan A., Binder, Mascha
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889203/
https://ncbi.nlm.nih.gov/pubmed/29632735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1417720
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