S181. THE STATE OR TRAIT COMPONENT OF DOPAMINE AND GLUTAMATE DYSFUNCTION IN THE RISK FOR PSYCHOSIS: AN IN VIVO MULTIMODAL IMAGING STUDY OF INDIVIDUALS WITH 22Q11.2 DELETION

BACKGROUND: Dopaminergic and glutamatergic dysregulation are among the leading hypotheses for schizophrenia. Previous in vivo imaging studies have shown that increased striatal presynaptic dopamine synthesis capacity (DSC) predates the onset of psychosis and is associated with symptom severity. Rece...

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Veröffentlicht in:Schizophr Bull
Hauptverfasser: Rogdaki, Maria, Veronese, Mattia, Hathway, Pamela, Jauhar, Sameer, Gudbrandsen, Maria, Daly, Eileen, Howes, Oliver
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5888616/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sby018.968
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