The relationship between cortical glutamate and striatal dopamine in first-episode psychosis: a cross-sectional multimodal PET and magnetic resonance spectroscopy imaging study

BACKGROUND: The pathophysiology of psychosis is incompletely understood. Disruption in cortical glutamatergic signalling causing aberrant striatal dopamine synthesis capacity is a proposed model for psychosis, but has not been tested in vivo. We therefore aimed to test the relationship between corti...

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Vydáno v:Lancet Psychiatry
Hlavní autoři: Jauhar, Sameer, McCutcheon, Robert, Borgan, Faith, Veronese, Mattia, Nour, Matthew, Pepper, Fiona, Rogdaki, M, Stone, James, Egerton, Alice, Turkheimer, Frederico, McGuire, Philip, Howes, Oliver D
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162342/
https://ncbi.nlm.nih.gov/pubmed/30236864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2215-0366(18)30268-2
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