O1.6. INCREASED COMPLEMENT FACTORS C3 AND C4 IN SCHIZOPHRENIA AND THE EARLY STAGES OF PSYCHOSIS: IMPLICATIONS FOR CLINICAL SYMPTOMATOLOGY AND CORTICAL THICKNESS

BACKGROUND: The complement system - a key component of the innate immune system, has been proposed to contribute to the pathogenesis of schizophrenia. Recently, complement C4 was associated with increased risk of schizophrenia, and in a mouse model, developmentally-timed synaptic pruning. These obse...

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Veröffentlicht in:Schizophr Bull
Hauptverfasser: Cropley, Vanessa, Laskaris, Liliana, Zalesky, Andrew, Weickert, Cynthia Shannon, Biase, Maria Di, Chana, Gursharan, Baune, Bernhard, Bousman, Chad, Nelson, Barnaby, McGorry, Patrick D, Everall, Ian, Pantelis, Christos
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5888408/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sby015.188
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