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Elevated peripheral expression of neuregulin-1 (NRG1) mRNA isoforms in clozapine-treated schizophrenia patients

Differential expression of neuregulin-1 (NRG1) mRNA isoforms and proteins has been reported in schizophrenia, primarily in post-mortem brain tissue. In this study, we examined 12 NRG1 SNPs, eight NRG1 mRNA isoforms (type I, type I((Ig2)), type II, type III, type IV, EGFα, EGFβ, pan-NRG1) in whole bl...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Mostaid, Md Shaki, Lee, Ting Ting, Chana, Gursharan, Sundram, Suresh, Shannon Weickert, Cynthia, Pantelis, Christos, Everall, Ian, Bousman, Chad
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802529/
https://ncbi.nlm.nih.gov/pubmed/29225331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-017-0041-2
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