F44. AN ADD-ON TRIAL WITH N-ACETYL-CYSTEINE (NAC) IN EARLY PSYCHOSIS PATIENTS: TOWARDS BIOMARKER GUIDED TREATMENT

BACKGROUND: Oxidative stress, coupled with dysregulation of inflammation, NMDAR and dopamine, is involved in schizophrenia (SZ) pathophysiology. Earlier add-on clinical trials showed in chronic SZ patients that NAC, a precursor of glutathione (GSH), an important cerebral antioxidant, improved negati...

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Publicado no:Schizophr Bull
Main Authors: Conus, Philippe, Fournier, Margot, Xin, Lijing, Cleusix, Martine, Baumann, Philipp S, Ferrari, Carina, Cousins, Ann, Alameda, Luis, Gholam-Razaee, Mehdi, Golay, Philippe, Jenni, Raoul, Woo, Tsung-Ung Wilson, Keshavan, Matcheri, Eap, Chin B, Wojcik, Joanne, Cuenod, Michel, Buclin, Thierry, Gruetter, Rolf, Seidman, Larry, Do, Kim
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5888404/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sby017.575
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https://ncbi.nlm.nih.gov/pmc/articles/PMC5888404/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sby017.575

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